Treatment of Sickle Cell Disease in Sub-Saharan Africa: We have come a long way, but still have far to go

Authors

  • Annette Akinsete National Director & Chief Executive Officer, Sickle Cell Foundation Nigeria, Idi-Araba, Lagos

DOI:

https://doi.org/10.51496/jogm.v2.79

Keywords:

sickle cell disease

References

Herrick JB. Peculiar elongated and sickle-shaped red blood corpuscles in a case of severe anaemia. Arch Intern Med (Chic) 1910; VI(5): 517–21. doi: 10.1001/archinte.1910.00050330050003 DOI: https://doi.org/10.1001/archinte.1910.00050330050003

Sickle Cell Association of New Jersey. A brief history of sickle cell disease. Available from: https://www.sicklecellnewjersey.org/about-scanj/history-of-sickle-cell [cited 20 October 2022].

Dennis-Antwi JA, Culley L, Hiles DR, Dyson SM. ‘I can die today, I can die tomorrow’: lay perceptions of sickle cell disease in Kumasi, Ghana at a point of transition. Ethn Health 2011; 16(4–5): 465–81. doi: 10.1080/13557858.2010.531249 DOI: https://doi.org/10.1080/13557858.2010.531249

Piel FB, Patil AP, Howes RE, et al. Global distribution of the sickle cell gene and geographical confirmation of the malaria hypothesis. Nat Commun 2010; 1: 104. doi: 10.1038/ncomms1104 DOI: https://doi.org/10.1038/ncomms1104

Jonxis J. Sickle cell gene in Indonesia. Nature 1957; 179: 876. doi: 10.1038/179876b0 DOI: https://doi.org/10.1038/179876b0

ENCYCLOPEDIA.com. Sickle cell disease. Available from: https://www.encyclopedia.com/medicine/encyclopedias-almanacs-transcripts-and-maps/sickle-cell-disease-0 [cited 23 October 2022].

Edelstein SJ. The sickled cell: from myth to molecules. Cambridge, MA: Harvard University Press; 1986. DOI: https://doi.org/10.4159/harvard.9780674189065

Debaun MR, Galadanci MA. Sickle cell disease in sub-Saharan Africa. UpToDate.com. Available from: https://www.uptodate.com/contents/sickle-celldisease-in-sub-saharan-africa [cited 23 October 2022].

World Health Organisation, African Region. Sickle Cell Disease – Fact Sheet. Available from: https://www.afro.who.int/health-topics/sickle-cell-disease [cited 20 October 2022].

Akinyanju OO. A profile of sickle cell disease in Nigeria. Ann N Y Acad Sci 1989; 565: 126–36. doi: 10.1111/j.1749-6632.1989.tb24159.x DOI: https://doi.org/10.1111/j.1749-6632.1989.tb24159.x

Nwabuko OC, Onwuchekwa U, Iheji O. An overview of sickle cell disease from the socio-demographic triangle – a Nigerian single-institution retrospective study. Pan Afr Med J 2022; 41: 161. doi: 10.11604/pamj.2022.41.161.27117 DOI: https://doi.org/10.11604/pamj.2022.41.161.27117

Nnodu OE, Oron AP, Sopekan A, Akaba GO, Piel FB, Chao DL. Child mortality from sickle cell disease in Nigeria: a model-estimated, population-level analysis of data from the 2018 Demographic and Health Survey. Lancet Haematol 2021; 8: e723–31. doi: 10.1016/S2352-3026(21)00216-7 DOI: https://doi.org/10.1016/S2352-3026(21)00216-7

Amarachukwu CN, Okoronkwo IL, Nweke MC, Ukwuoma MK. Economic burden and catastrophic cost among people living with sickle cell disease, attending a tertiary health institution in south-east zone, Nigeria. PLoS One 2022; 17(8): e0272491. doi: 10.1371/journal.pone.0272491 DOI: https://doi.org/10.1371/journal.pone.0272491

Colombatti R, Sainati L. Management of children with sickle cell disease in Europe: current situation and future perspectives. EMJ Hematol 2016; 4(1): 129–35. doi: 10.33590/emjhematol/10310534 DOI: https://doi.org/10.33590/emjhematol/10310534

Sickle Cell Association of New Jersey. Timeline of sickle cell disease. Available from: https://www.sicklecellnewjersey.org/timeline-of-sickle-cell-disease. [cited 26 October 2022].

Ali MA, Ahmad A, Chaudry H, et al. Efficacy and safety of recently approved drugs for sickle cell disease: a review of clinical trials. Exp Hematol 2020; 92: 11–18.e1. doi: 10.1016/j.exphem.2020.08.008 DOI: https://doi.org/10.1016/j.exphem.2020.08.008

United Nations General Assembly. A/RES/63/237. Resolution adopted by the General Assembly on 22 December 2008. Available from: https://digitallibrary.un.org/ [cited 26 October 2022].

Gardner K, Douiri A, Drasar E, et al. Survival in adults with sickle cell disease in a high-income setting. Blood 2016; 128(10): 1436–8. doi: 10.1182/blood-2016-05-716910 DOI: https://doi.org/10.1182/blood-2016-05-716910

Regional Committee for Africa, 60. Sickle-cell disease: a strategy for the WHO African region. 2011. Available from: https://apps.who.int/iris/handle/10665/1682 [cited 26 October 2022].

Kasai ET, Alworong’a Opara JP, Ntokamunda Kadima J, Kalenga M, Batina Agasa S, Marini Djang’eing’a R. Overview of current progress and challenges in diagnosis, and management of pediatric sickle cell disease in Democratic Republic of the Congo. Hematology 2022; 27(1): 132–40. doi: 10.1080/16078454.2021.2023399 DOI: https://doi.org/10.1080/16078454.2021.2023399

Ofakunrin AO, Okpe ES, Afolaranmi TO, et al. Level of utilization and provider-related barriers to the use of hydroxyurea in the treatment of sickle cell disease patients in Jos, North-Central Nigeria. Afr Health Sci 2021; 21(2): 765–74. doi: 10.4314/ahs.v21i2.36 DOI: https://doi.org/10.4314/ahs.v21i2.36

Speid L. Sickle Cell Disease — The New Frontier! Putting Rare Diseases Patients First! (PRDPF!). Available from: https://puttingrarediseasespatientsfirst.org/sickle-cell-disease-the-new-frontier/ [cited 1 November 2022].

World Health Organisation – Fact Sheets. Universal Health Coverage. Available from: https://www.who.int/news-room/fact-sheets/detail/universal-health-coverage-(uhc) [cited 1 November 2022].

Published

23-12-2022

How to Cite

Akinsete, A. (2022). Treatment of Sickle Cell Disease in Sub-Saharan Africa: We have come a long way, but still have far to go. Journal of Global Medicine, 2(1), e79. https://doi.org/10.51496/jogm.v2.79